DEVELOPMENT AND CHARACTERIZATION OF POTENTIAL OCULAR MUCOADHESIVE NANO LIPID CARRIERS USING FULL FACTORIAL DESIGN

Development and Characterization of Potential Ocular Mucoadhesive Nano Lipid Carriers Using Full Factorial Design

Generally, topically applied eye drops have low bioavailability due to short residence time and low penetration of the drug.The aim of the present study was to incorporate dexamethasone (DXM) into nano lipid carriers (NLC), which contain mucoadhesive polymer, in order to increase the bioavailability of the drug.A 23 factorial experimental design wa

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Are the Effects of Oral and Vaginal Contraceptives on Bone Formation in Young Women Mediated via the Growth Hormone-IGF-I Axis?

Purpose: Combined hormonal contraceptive therapy has been associated with negative bone mineral density outcomes that may be route-dependent [i.e., combined oral Anti-bacterials contraception (COC) vs.contraceptive vaginal ring (CVR)] and involve the hepatic growth hormone (GH)/insulin-like growth factor-I (IGF-I) axis.The objective of the pilot st

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Comparison of the Time-Dependent Changes in Immediate Early Gene Labeling and Spine Density Following Abstinence From Contingent or Non-contingent Chocolate Pellet Delivery

Rationale: Incubation of craving is a phenomenon whereby responding for cues associated with a reward increases over extended periods of abstinence.Both contingent and non-contingent behavioral designs have been used to study the incubation of craving phenomenon with differing results.The present study directly compares behavioral and neural change

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Effects of lift-assist device on trunk and shoulder kinematics

Background: Repetitive handling of heavy concrete blocks has been associated with the risk of low back and shoulder injuries among the masons.Several interventions have been proposed to reduce the risk of musculoskeletal disorders among the masons.A new intervention, a lift-assist handle, was tested in this study.Objective: The effectiveness of the

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Molecular Analysis of South African Ovine Herpesvirus 2 Strains Based on Selected Glycoprotein and Tegument Genes.

Ovine herpesvirus 2 (OvHV-2), is the causative agent of sheep-associated malignant catarrhal fever (SA-MCF), a generally Beko ASL1331PX Stainless Steel American Fridge Freezer fatal disease of cattle and other captive wild ruminants.Information on the OvHV-2 strains circulating in South Africa (SA) and other African countries with regard to genetic

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